David A Fidock Selected Research

SJ733

12/2014

(+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium.

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David A Fidock Research Topics

Disease

107	Malaria 04/2024 - 04/2002
25	Infections 01/2023 - 11/2006
17	Falciparum Malaria (Plasmodium falciparum Malaria) 01/2022 - 10/2002
4	Parasitemia 09/2023 - 07/2011
2	Starvation 01/2024 - 07/2023
2	Coinfection 07/2015 - 11/2014
1	Neoplasms (Cancer) 01/2021
1	Pneumonia (Pneumonitis) 01/2021
1	Communicable Diseases (Infectious Diseases) 11/2019
1	Vivax Malaria 01/2018
1	Hemolysis 11/2014
1	Body Weight (Weight, Body) 02/2012

Drug/Important Bio-Agent (IBA)

43	Antimalarials (Antimalarial Agents)IBA 04/2024 - 10/2002
33	artemisinin (artemisinine)IBA 04/2024 - 10/2002
18	Chloroquine (Aralen)FDA LinkGeneric 12/2019 - 10/2002
10	Proteins (Proteins, Gene)FDA Link 09/2023 - 08/2006
7	ArtesunateIBA 09/2023 - 08/2006
6	piperaquineIBA 10/2023 - 08/2011
5	DSM265IBA 01/2021 - 07/2015
4	ArtemisininsIBA 03/2024 - 01/2016
4	Amino Acids FDA Link 01/2024 - 05/2015
4	Dihydroorotate DehydrogenaseIBA 01/2021 - 07/2015
4	Quinine (Quinson)FDA Link 06/2009 - 10/2002
3	Peptide Elongation Factor 2 (EF-2)IBA 10/2023 - 01/2015
3	MMV390048IBA 12/2020 - 01/2017
3	Mefloquine (Lariam)FDA LinkGeneric 01/2017 - 07/2006
3	Fatty Acids (Saturated Fatty Acids)IBA 05/2014 - 04/2002
2	asparaginyl-tRNA synthetaseIBA 01/2024 - 07/2023
2	Lumefantrine Drug Combination Artemether (Coartem)FDA Link 09/2023 - 03/2009
2	Amodiaquine (Camoquin)FDA Link 09/2023 - 10/2002
2	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2023 - 01/2019
2	artenimol (dihydroartemisinin)IBA 11/2022 - 01/2017
2	VaccinesIBA 01/2022 - 01/2020
2	1-Phosphatidylinositol 4-Kinase (1 Phosphatidylinositol 4 Kinase)IBA 12/2020 - 01/2018
2	ganaplacideIBA 01/2020 - 09/2014
2	alpha-aminopyridineIBA 01/2018 - 01/2017
2	2- methyl- 3- (4- phenylpiperidino)propionohydroxamic acid hydrochloride (K 76)IBA 09/2015 - 03/2009
2	Drug CombinationsIBA 07/2015 - 01/2014
2	Triclosan (pHisoHex)FDA Link 02/2013 - 01/2011
2	pyrimethamine drug combination fanasil (Fansidar)FDA Link 12/2009 - 06/2008
1	acetamideIBA 03/2024
1	Histidine (L-Histidine)FDA Link 09/2023
1	Mupirocin (Bactroban)FDA LinkGeneric 01/2023
1	reveromycin AIBA 01/2023
1	1,2,3,4-tetrahydroquinolineIBA 11/2022
1	Aspartic Acid ProteasesIBA 10/2022
1	plasmepsin (plasmepsin I)IBA 10/2022
1	sapanisertibIBA 10/2022
1	ZY-19489IBA 01/2022
1	Acetate-CoA Ligase (Acetyl CoA Synthetase)IBA 01/2022
1	Heme (Haem)IBA 11/2021
1	octaneIBA 01/2021
1	hemozoinIBA 01/2021
1	Bortezomib (Velcade)FDA Link 01/2021
1	InsecticidesIBA 01/2021
1	AntibodiesIBA 01/2020
1	GNF 179IBA 01/2020
1	Glutamic Acid (Glutamate)FDA Link 01/2020
1	artesunate drug combination pyronaridine tetraphosphateIBA 01/2020
1	ProteomeIBA 01/2020
1	AntigensIBA 01/2020
1	4-aminoquinolineIBA 12/2019
1	proguanil drug combination atovaquone (malarone)FDA Link 01/2019
1	Biomarkers (Surrogate Marker)IBA 02/2017
1	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 01/2017
1	Zinc Finger NucleasesIBA 11/2016
1	ACT-451840IBA 10/2016
1	Plasmodium falciparum PfCRT proteinIBA 09/2015
1	EnzymesIBA 07/2015
1	pyrimidineIBA 07/2015
1	Codon (Codons)IBA 05/2015
1	Equilibrative Nucleoside Transporter 1IBA 03/2015
1	Messenger RNA (mRNA)IBA 01/2015
1	Guanosine Triphosphate (GTP)IBA 01/2015
1	DDD107498IBA 01/2015
1	SJ733IBA 12/2014
1	IronIBA 11/2014
1	Dextrans (Dextran)FDA Link 11/2014
1	Anti-Bacterial Agents (Antibiotics)IBA 11/2014
1	Hemin (Panhematin)FDA Link 08/2014
1	Folic Acid (Vitamin M)FDA LinkGeneric 07/2014
1	succinyl-trialanine-4-nitroanilide (SANA)IBA 01/2014
1	pyronaridineIBA 01/2014
1	Phosphotransferases (Kinase)IBA 12/2013
1	LipidsIBA 12/2013
1	LuciferasesIBA 12/2013
1	Serine (L-Serine)FDA Link 11/2013
1	phosphoethanolamine methyltransferaseIBA 11/2013
1	Phosphatidylcholines (Phosphatidylcholine)IBA 11/2013
1	Glutathione (Reduced Glutathione)IBA 12/2012
1	solithromycinIBA 02/2012
1	KitasamycinIBA 10/2011
1	Amlodipine (Norvasc)FDA LinkGeneric 07/2011
1	Azithromycin (Zithromax)FDA LinkGeneric 07/2011
1	AnionsIBA 05/2011

Therapy/Procedure

32	Therapeutics 02/2024 - 08/2006
4	Drug Therapy (Chemotherapy) 01/2021 - 11/2006
1	Chemoprevention 11/2022
1	Oral Medicine 01/2018
1	Aftercare (After-Treatment) 08/2011